Many people suffer from isolation and loneliness with their negative effects.  To be lonely is not to have significant companionship at the moment. There is something missing in one's life. Loneliness can make one feel alone. Aloneness, on the other hand, could be a preparation for a different type of relationship, namely with God. We are called to separate ourselves from the many distractions of the world in  order to be alone with God. In this way we will be better able to experience God in a new way. Jesus invites us to come aside from our busyness and be still and know that he is God.